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    Your target dosage form. Your release properties.

    Excipients for Drug Formulation Instant & Modified Release Platform


    Instant & Modified Release

    BASFs rich portfolio of instant and modified release solutions offers an unprecedented range of functionality. Our high-quality, industry-leading products enable you to formulate pharmaceuticals with the exact release properties you desire. This ensures the right results every time – giving you that all-important competitive edge.

    We are a trusted industry player with a proven track record, going back to the invention of PVP (marketed under the brand name Kollidon®) in the 1930s. And we have continued to expand and enhance our portfolio ever since – with innovative, multifunctional excipients such as Kollicoat® IR, Kollidon® VA64 and Ludiflash®. BASFs rich portfolio of instant and modified release solutions offers an unprecedented range of functionality. These products reflect our dedication to highly effective, reliable and resource-efficient solutions that help you confidently design the dosage form that you need.

    Benefit from BASFs comprehensive range
    Widest functional offer range for Instant & Modified
    release in the industry
    Functional solutions for solid and liquid
    dosage forms
    Create your dosage form with instant, enteric or
    sustained drug release

    Solutions for key release profiles.

    Functional solutions for key processing technologies to create Instant & Modified Release Profiles.

    Webinars

    Successful Binding of Peroxide Sensitive APIs

    In this live webinar, experts will showcase how to formulate a peroxide-sensitive drug using a binder that combines high binding strength with no peroxide formation at all.

    Maximizing Roller Compaction Benefits with Proper Excipient Selection

    The pharmaceutical industry has adopted roller compaction due to its significant advantage in production process efficiency and its applicability for specific APIs. This webinar will explain formulation practices using roller compaction.

    Product Innovation on Modified Release Coatings (Sustained Release and Enteric Coatings)

    Developing modified coatings that produce a reliable and stable release is still a challenge. Only a few polymers - polyvinylacetate, ethylcellulose and methacrylates - are suitable for this purpose and have very different characteristics. In this webinar, you will gain an in-depth knowledge about the relevant requirements for modified release coatings and how they can be fulfilled, for instance by choosing a suitable polymer, the proper formulation and the best process parameters.

    BASF Pharma solutions for Orally Disintegrating Tablets

    ODTs are becoming increasingly popular for various reasons. For the consumer or patient, they offer a much more convenient administration, while healthcare companies can use them to differentiate their offer by creating line extensions. In this webinar you will learn about three approaches to develop an ODT – direct compression, granulation & tableting and ready-to-use - and the pros and cons they offer. We will provide guidance on how to choose the right approach for your project, and will support this with a case study as well as an in-depth look at the selection of specific formulation components.

    Articles

    A Recent Advancement in Orally Disintegrating Formulations

    Orally disintegrating tablets (ODT) or sublingual technologies have drawn attention in the industry as a promising approach to deliver drugs in life cycle management to a wide range of the patient population. Those technologies are also aimed at patients incapable of swallowing pills, especially in pediatric and geriatric populations. The criteria for rapid dissolution and onset of active ingredients in an ODT dosage depends on the performances of individual excipients which must qualify 3 unique criteria: (i) hydrophilic in nature, (ii) dissolves quickly with good mouth feel, and (iii) is highly compressible. Identifying such excipients and/or technologies to meet these criteria could be challenging, especially to overcome the drug’s loading and stability.

    Controlled Release: A New Paradigm with Polyvinyl Acetate Polymer

    Controlled release (CR) has been a subject of continued interest, and the pharma industry is taking a closer look into release profiles of drugs because of risk factors associated with early release (dose dumping) before being delivered to intended sites to achieve the desired efficacy, and to overcome toxicity and drug abuse issues. The latter has become more challenging, especially in controlled delivery of opioids in pain management. Nonetheless, the former one is also poorly understood because of complexity associated with the mechanism of controlled release from a particular dosage.

    Whitepapers

    The Binding of Peroxide-Sensitive APIs: Typical Challenges, and How to Overcome Them

    Excipients are crucial for effective drug formulation, and excipient manufacturers continue to make advances in technology designed to address the formulation challenges presented by new drug substances. Pharmaceutical Technology magazine talked with Dr. Bernhard Fussnegger, Global Development and Technical Marketing at BASF, about the excipient developer’s family of peroxide-free excipients that are recommended for APIs sensitive to oxidation.

    Maximizing Roller Compaction Benefits with the Proper Excipient Selection

    Roller compaction is employed by the pharmaceutical industry due to the significant advantages it offers in production process efficiency and its applicability for specific APIs. In this whitepaper, a drug development expert will explain when and why roller compaction is used and summarize the key benefits for both the formulator as well as the production team. Participants will learn the key factors to consider when selecting the excipients for optimal compaction results and review examples of different applications.

    Podcasts

    Binding of peroxide sensitive API – typical challenges and how to overcome them

    Excipients are crucial for effective drug formulation, and excipient manufacturers continue to make advances in technology designed to address the formulation challenges presented by new drug substances. Pharmaceutical Technology magazine talked with Dr. Bernhard Fussnegger, Global Development and Technical Marketing at BASF, about the excipient developer’s family of peroxide-free excipients that are recommended for APIs sensitive to oxidation.